In the occupied West Bank, an Israeli-American was shot and killed as retaliatory unrest grew worse.
The man was killed during an assault on passing cars on a highway close to Jericho.
After Israeli settlers attacked Palestinian villages in the West Bank on Sunday night, burning dozens of cars and homes, the shooting took place.
Following the Sunday shooting deaths of two settlers from a nearby village by a Palestinian, that attack occurred.
Paramedics transported the Israeli-American victim of the shooting near Jericho to a Jerusalem hospital, but he was later declared dead.
"Unfortunately, I can confirm that a US citizen was killed in one of the terror attacks in the West Bank tonight," US Ambassador Tom Nides wrote in a tweet. For his family, I pray. ".
Attackers reportedly opened fire on Israeli vehicles three times before setting their own vehicles on fire, according to the Israeli Defense Forces.
The attackers engaged in a firefight with police before running away, the IDF tweeted.
No Palestinian organizations immediately took responsibility for the incident.
Hamas, an Islamist organization that dominates the Gaza Strip but is less well-known in the West Bank, claimed that the attack was a normal reaction to Israeli attacks.
According to a spokesman, "the crimes committed by the occupation and the herds of settlers will not be met with anything less than stabbing, shooting, and car ramming.".
Following a summit in Jordan, where Israeli and Palestinian officials promised to defuse tensions, violence broke out.
A large group of Israeli settlers entered the village of Hawara, about 4 miles (6 km) south of Nablus, in videos that were published hours after the summit ended on Sunday. They lit fires and threw stones as they entered the village.
According to the Palestinian Health Ministry, Sameh Aqtash, 37, passed away on Sunday night after being shot in the stomach by settlers during an attack in Zaatara.
Israeli control over this region of the West Bank is total, and Palestinians have criticized Israeli security forces for failing to protect them.
According to Mahmoud Abbas, president of the Palestinian Authority, "the terrorist acts carried out by Israeli settlers, under the protection of the Israeli occupation forces," are entirely the responsibility of the Israeli government.
Benjamin Netanyahu, the prime minister of Israel, pleaded for peace and urged settlers to refrain from violence so that the Israeli military and security forces could concentrate on apprehending the shooter who killed the two Israelis.
In a video statement, he pleaded with people not to use the law when the situation was tense and the blood was boiling.
In order to "seek revenge" for the fatal attack on Hillel and Yagel Yaniv, who lived in the settlement of Har Bracha, 1 point 2 miles south of Nablus, settlers had called for a march to Hawara.
When a Palestinian man rammed the brothers' car and then opened fire on them both multiple times, they were traveling through Hawara.
Although no Palestinian militant group has so far claimed responsibility for the attack, the shooter was reportedly sporting a shirt bearing the logo of the Lions' Den, a Nablus-based organization.
Last Wednesday, members of the group were the target of an Israeli raid in Nablus that claimed the lives of 11 Palestinians, including a number of civilians. This operation has been the deadliest in the West Bank since 2005.
In an effort to stop the recent wave of deadly attacks by Palestinians against Israelis, Israeli forces have been conducting waves of search, arrest, and intelligence gathering raids in Nablus and the nearby city of Jenin.
Over 60 Palestinians, including militants and civilians, have been killed by Israeli forces since the year's beginning. On the Israeli side, 14 people—all civilians with the exception of a paramilitary police officer—have been killed in attacks.
140 settlements established since Israel's occupation of the West Bank and East Jerusalem during the Middle East War in 1967 are home to more than 600,000 Jews.
Although Israel disputes this, the majority of the international community views the settlements as being against international law.