According to the streaming service, The Weeknd is the first artist ever to reach 100 million monthly listeners.
Blinding Lights, which has been heard 3.4 billion times on the service, is the artist's most played song of all time.
A new remix of Die For You featuring Ariana Grande was released a few days prior to receiving his most recent honor.
The 2016 song has experienced newfound success since going viral on TikTok.
It was a modest hit when it was first released, peaking at number 74 on the charts. Last week, it returned to the Top 40 and is expected to soar this Friday.
The Weeknd, whose real name is Abel Tesfaye, has amassed more than 45 platinum singles and albums, making him one of the biggest chart stars of the past ten years.
In 2010, he posted his first songs to YouTube, showcasing a dark, explicit strand of R&B that explored drug use, casual sex, and alienation. He was born in Toronto to immigrants from Ethiopia.
Drake, a Canadian rapper, posted those early demos to his personal blog, which caused his popularity to soar and enabled Tesfaye to create the nine-song mixtape House of Balloons, which he made available as a free download.
Tesfaye appeared to be an unlikely candidate for mainstream success despite positive reviews, but by the middle of the 2010s, he had amassed an astonishing string of hit singles.
These included a duet with Ariana Grande called "Love Me Harder," a disco-funk hit called "I Can't Feel My Face," and a futuristic partnership with Daft Punk called "Starboy.".
The lead single from his fourth studio album After Hours, Blinding Lights, held the top five spot on the US Hot 100 for the longest period of time.
A character's hedonistic night out takes a dark turn in the concept album After Hours, which features alcohol, a fight, and ultimately possession by an evil spirit. Throughout the entire publicity campaign, Tesfaye maintained his character while wearing bandages over his face.
The story was continued in the sequel released the previous year, Dawn FM, with the main character passing through purgatory on his way to heaven.
The album went to number one in the UK for the third time for the celebrity, adding to a list of accomplishments that already included four Grammy Awards, two MTV Awards, and an Oscar nomination for Earned It, a song he contributed to the soundtrack for the film Fifty Shades of Grey.
The Weeknd is the first artist to reach 100 million monthly listeners on Spotify, which has a market share of about 30% globally and 50% in the UK.
The Beatles have 27 million monthly listeners, Madonna has 23 million, and Michael Jackson has 34 million, to put that into perspective.
Miley Cyrus, who trails Tesfaye by 82.5 million despite the record-breaking success of her most recent single, Flowers, is her closest rival.
The musician would have made $239,072 (£198,176) in revenue last month if each of his 100,450,642 listeners had played just one of his songs.
Die For You, which was overlooked upon release, has found new life on TikTok, where it soundtracks more than 150,000 videos.
Unusually, the song doesn't have a meme or dance that has gone viral. Simply put, people are addicted to its overwrought R.
The song has returned to the US charts, where it is currently at number seven, thanks to the unanticipated resurgence.
The Weeknd has taken advantage of the situation by releasing a remix with Ariana Grande, with whom he has performed duets four times.
With a video of herself in the studio working on the track, Grande teased the release last week.
She referred to her part in the upcoming Wicked movie, saying, "Wrote and recorded a verse for my friend after a 14-hour day on set.". "This particular exception needed to be made. " .
The Weeknd: Live at SoFi Stadium, a concert movie shot during the American leg of his ongoing After Hours 'Til Dawn Tour, was made public over the weekend by the celebrity.
This summer, the show will make its way to Europe, stopping in the UK for performances at the Olympic Stadium in London and Manchester's Etihad Stadium.
The musician is currently getting ready to release The Idol, a TV drama he co-wrote with Sam Levinson of Euphoria.
The program will tell the tale of "a self-help guru and the head of a contemporary cult, who forges a complicated bond with a budding pop idol. ".
Although a release date hasn't been set, a trailer debuted last October, showcasing an all-star cast that includes Hank Azaria from The Simpsons, Troye Sivan, Dan Levy from Schitt's Creek, Jennie from Blackpink, and Lily-Rose Depp.